Leonard A. Lauder, the art patron and philanthropist who with his mother, Estée Lauder, built a family cosmetics business into a worldwide organization of brands, died on June 7 at his home on the Upper East Side of Manhattan. He was 92.

While best known for his business enterprises, Mr. Lauder was also one of America’s most influential philanthropists and art patrons. He gave hundreds of millions to museums, medical institutions and breast cancer and Alzheimer’s research, as well as to other cultural, scientific and social causes.

In 2013, he pledged the most significant gift in the history of the Metropolitan Museum of Art, a trove of nearly 80 Cubist paintings, drawings and sculptures by Picasso, Braque, Léger and Gris. Scholars put the value of the gift at $1 billion and said its quality rivaled or surpassed that of the collections of the MOMA in New York, the State Hermitage Museum in St. Petersburg, Russia, and the Pompidou Center in Paris.

Estée Lauder’s sales, which hovered around $800,000 a year when Mr. Lauder joined the company, soared to more than $16 billion for fiscal 2021. Mr. Lauder’s personal fortune has been estimated at about 10.1 billion, according to Forbes, making him one of the 100 richest Americans.

For all his contributions to various causes, Mr. Lauder regarded himself as a frugal man with an eye on the bottom line. “I use slivers of soap, I reuse paperclips, I use the backside of memos,” he told The New York Times in 2004. “You can take the child out of the Depression, but you can’t take the Depression out of the child.”